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March 14, 2008

Two Parents With Alzheimer's Raises Child's Risk

Any additional family history boosts odds of getting the disease earlier, study finds

URL of this page: http://www.nlm.nih.gov/medlineplus/news/fullstory_62040.html  (*this news item will not be available after 06/08/2008)

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HealthDayMonday, March 10, 2008

HealthDay news imageMONDAY, March 10 (HealthDay News) -- If both parents have Alzheimer's disease, their children face an increased risk of developing the condition, a new study suggests.

Overall, 42 percent of offspring whose parents both had Alzheimer's went on to develop the disease themselves by age 70, the researchers found.

The risk is also greater of developing the disease early if additional relatives had Alzheimer's disease, researchers say.

Most experts agree that genetics plays a role in Alzheimer's disease, but the degree to which genetics is responsible for the disease is still unclear.

Bird's group is trying to determine the genetic factors at play in Alzheimer's disease. So far, only one genetic factor has been documented, Bird said. "The hope is, there will be others and they will be found," he said. "Presumably, these children would have a higher concentration of those factors. So, that's what ought to be looked for."

The report appears in the March issue of the Archives of Neurology.

In the study, Bird's team collected data on the grown children in 111 families where both parents had Alzheimer's disease.

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